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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
28.48
Human Site:
S124
Identified Species:
44.76
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
S124
L
V
R
D
V
V
S
S
L
R
R
H
R
M
H
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
S124
L
V
R
D
V
V
S
S
L
R
R
H
R
M
H
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
S124
L
V
R
D
V
V
S
S
L
R
R
H
R
M
H
Dog
Lupus familis
XP_533920
792
88144
S124
L
V
R
D
V
V
S
S
L
R
R
H
R
M
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
S124
L
I
R
D
V
V
S
S
L
R
R
H
R
M
H
Rat
Rattus norvegicus
NP_001011980
470
52521
S124
L
I
R
D
V
V
S
S
L
R
R
H
R
M
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
A124
L
I
K
D
V
I
S
A
L
R
R
H
R
M
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
S123
L
I
K
D
N
I
S
S
L
K
R
H
R
M
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
L123
L
A
R
D
V
I
S
L
S
K
K
Q
M
I
D
Honey Bee
Apis mellifera
XP_395421
413
48031
S121
V
T
H
M
C
I
F
S
K
T
E
Q
G
M
Y
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
C151
L
A
R
H
V
V
N
C
Q
K
R
P
V
A
T
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
Q13
S
K
S
K
K
A
A
Q
R
K
Q
N
L
A
E
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
K9
F
V
K
P
I
V
K
K
K
Q
A
N
V
D
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
L58
L
Q
M
D
L
R
K
L
M
L
P
Y
T
A
L
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
K121
Y
S
L
G
R
D
I
K
K
F
L
K
R
P
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
N.A.
N.A.
66.6
N.A.
33.3
13.3
33.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
60
33.3
46.6
26.6
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
7
7
7
0
0
7
0
0
20
0
% A
% Cys:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
67
0
7
0
0
0
0
0
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% E
% Phe:
7
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
7
7
0
0
0
0
0
0
0
54
0
0
60
% H
% Ile:
0
27
0
0
7
27
7
0
0
0
0
0
0
7
0
% I
% Lys:
0
7
20
7
7
0
14
14
20
27
7
7
0
0
7
% K
% Leu:
74
0
7
0
7
0
0
14
54
7
7
0
7
0
7
% L
% Met:
0
0
7
7
0
0
0
0
7
0
0
0
7
60
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
0
14
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
7
7
0
7
0
% P
% Gln:
0
7
0
0
0
0
0
7
7
7
7
14
0
0
0
% Q
% Arg:
0
0
54
0
7
7
0
0
7
47
60
0
60
0
0
% R
% Ser:
7
7
7
0
0
0
60
54
7
0
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
0
0
7
0
7
% T
% Val:
7
34
0
0
60
54
0
0
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _